S4 Andarine, also known as Andarine or S-4, is a selective androgen receptor modulator (SARM) that was originally developed for the treatment of conditions like muscle wasting, osteoporosis, and other disorders related to muscle and bone loss. It has gained popularity in bodybuilding and fitness communities due to its potential ability to enhance muscle growth and fat loss with fewer side effects compared to anabolic steroids.
Key Features of S4 Andarine:
Mechanism of Action: S4 selectively binds to androgen receptors in muscle and bone tissues, promoting an increase in lean muscle mass and enhancing bone strength without significantly affecting other tissues, such as the prostate or hair follicles.
Benefits:
Muscle Growth: Andarine is known for promoting lean muscle mass by increasing muscle protein synthesis.
Fat Loss: It may help with fat loss, especially in the abdominal region, by improving fat oxidation and metabolism.
Increased Strength: Some users report improved strength and athletic performance.
Bone Health: It can enhance bone density and strength, potentially benefiting individuals with bone-related issues.
Side Effects:
Vision Changes: One of the most notable side effects of S4 is its impact on vision. Users have reported a yellow tint to vision and reduced night vision, which is typically temporary and reversible after discontinuation.
Testosterone Suppression: Like other SARMs, S4 may suppress natural testosterone production, especially when used in high doses or for extended periods.
Liver Toxicity: Though less liver-toxic than some other compounds, there are concerns about long-term liver health when using S4, particularly in high doses.
Half-Life: S4 has a relatively short half-life (about 4-6 hours), which means it may need to be dosed multiple times throughout the day.
Legal Status: S4 is not approved for human consumption by regulatory agencies like the FDA, and it is often sold as a research chemical. It is banned in competitive sports by organizations like WADA (World Anti-Doping Agency).